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Li Pan Selected Research

silvestrol

1/2020Targeting Protein Translation by Rocaglamide and Didesmethylrocaglamide to Treat MPNST and Other Sarcomas.
1/2018Overexpression of eIF4F components in meningiomas and suppression of meningioma cell growth by inhibiting translation initiation.
1/2016Silvestrol induces early autophagy and apoptosis in human melanoma cells.
1/2016Components of the eIF4F complex are potential therapeutic targets for malignant peripheral nerve sheath tumors and vestibular schwannomas.
2/2015The translation inhibitor silvestrol exhibits direct anti-tumor activity while preserving innate and adaptive immunity against EBV-driven lymphoproliferative disease.
3/2013Silvestrol exhibits significant in vivo and in vitro antileukemic activities and inhibits FLT3 and miR-155 expressions in acute myeloid leukemia.
9/2012Dual targeting of the cyclin/Rb/E2F and mitochondrial pathways in mantle cell lymphoma with the translation inhibitor silvestrol.
9/2011Resistance to the translation initiation inhibitor silvestrol is mediated by ABCB1/P-glycoprotein overexpression in acute lymphoblastic leukemia cells.

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Li Pan Research Topics

Disease

58Neoplasms (Cancer)
01/2022 - 02/2003
19Infections
01/2022 - 07/2006
16Hypertension (High Blood Pressure)
10/2022 - 06/2010
13Breast Neoplasms (Breast Cancer)
01/2021 - 05/2006
12Neoplasm Metastasis (Metastasis)
01/2022 - 01/2012
11Inflammation (Inflammations)
01/2022 - 01/2016
7Obesity
10/2022 - 01/2012
6Foot-and-Mouth Disease
05/2022 - 01/2008
6Nasal Polyps (Nasal Polyp)
01/2022 - 01/2020
6HIV Infections (HIV Infection)
10/2021 - 01/2018
6Hypoxia (Hypoxemia)
01/2021 - 07/2009
6Colonic Neoplasms (Colon Cancer)
07/2017 - 04/2010
5Dyslipidemias (Dyslipidemia)
10/2022 - 01/2012
5Ischemia
01/2022 - 01/2017
5COVID-19
01/2022 - 01/2021
5Glioma (Gliomas)
02/2021 - 07/2010
5Carcinogenesis
01/2021 - 05/2010
5Asthma (Bronchial Asthma)
01/2021 - 05/2008
5Wounds and Injuries (Trauma)
01/2021 - 01/2015
5Lung Neoplasms (Lung Cancer)
01/2021 - 01/2018
5Hyperoxia
08/2009 - 10/2006
4Glioblastoma (Glioblastoma Multiforme)
04/2022 - 03/2016
4Pain (Aches)
01/2022 - 08/2006
4Metabolic Syndrome (Dysmetabolic Syndrome X)
01/2021 - 01/2012
4Carcinoma (Carcinomatosis)
01/2021 - 04/2010
4Virus Diseases (Viral Diseases)
01/2021 - 11/2017
4False Aneurysm (Pseudoaneurysm)
01/2021 - 09/2013
4Cardiovascular Diseases (Cardiovascular Disease)
12/2020 - 03/2018
4Myocardial Infarction
12/2020 - 08/2006
4Prehypertension
11/2019 - 01/2017
4Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
10/2015 - 09/2011
4Leukemia
03/2013 - 09/2010
4Lung Diseases (Lung Disease)
08/2009 - 10/2006
3Overweight
10/2022 - 01/2018
3Coronary Disease (Coronary Heart Disease)
11/2021 - 01/2021
3Rhinosinusitis
01/2021 - 01/2020
3Squamous Cell Carcinoma of Head and Neck
01/2021 - 02/2016
3Triple Negative Breast Neoplasms
05/2020 - 10/2014
3Reperfusion Injury
01/2020 - 01/2017
3Human Influenza (Influenza)
01/2019 - 01/2018
3Squamous Cell Carcinoma (Epidermoid Carcinoma)
09/2018 - 05/2010
3Ovarian Neoplasms (Ovarian Cancer)
01/2017 - 04/2010
3Brain Edema (Cerebral Edema)
01/2016 - 08/2003
3Hepatocellular Carcinoma (Hepatoma)
04/2015 - 08/2013
3Necrosis
09/2014 - 08/2011
3Infarction (Infarctions)
11/2013 - 10/2006
2Bites and Stings (Sting)
11/2022 - 01/2021

Drug/Important Bio-Agent (IBA)

22Proteins (Proteins, Gene)FDA Link
11/2022 - 01/2010
13Biomarkers (Surrogate Marker)IBA
01/2021 - 08/2011
10Pharmaceutical PreparationsIBA
01/2022 - 03/2010
9VaccinesIBA
05/2022 - 01/2010
9MicroRNAs (MicroRNA)IBA
01/2021 - 01/2014
8silvestrolIBA
01/2020 - 09/2011
6Messenger RNA (mRNA)IBA
12/2021 - 02/2003
6Biological ProductsIBA
09/2021 - 03/2013
6SurvivinIBA
01/2021 - 01/2010
6Interleukin-6 (Interleukin 6)IBA
01/2021 - 09/2012
6Liposomes (Liposome)IBA
01/2012 - 01/2010
5Phosphotransferases (Kinase)IBA
11/2022 - 01/2017
5Triglycerides (Triacylglycerol)IBA
10/2022 - 06/2010
5Retinaldehyde (Retinal)IBA
01/2022 - 01/2017
5CytokinesIBA
01/2022 - 01/2005
5Small Interfering RNA (siRNA)IBA
01/2021 - 07/2010
5ORALIT (ORS)IBA
11/2019 - 01/2017
5AntigensIBA
01/2019 - 01/2015
4AerosolsIBA
12/2021 - 03/2003
4Indicators and Reagents (Reagents)IBA
10/2021 - 05/2010
4HDL CholesterolIBA
05/2021 - 06/2010
4AntioxidantsIBA
01/2021 - 03/2009
4Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2021 - 08/2012
4Bevacizumab (Avastin)FDA Link
01/2020 - 08/2012
4Saline SolutionIBA
01/2012 - 05/2010
41,2- dioleoyloxy- 3- (trimethylammonium)propaneIBA
01/2012 - 01/2010
3Uric Acid (Urate)IBA
10/2022 - 01/2021
3Glucose (Dextrose)FDA LinkGeneric
07/2022 - 01/2012
3Eukaryotic Initiation Factor-4EIBA
02/2022 - 01/2016
3Tissue Plasminogen Activator (Alteplase)FDA Link
01/2022 - 01/2020
3LipidsIBA
01/2022 - 01/2019
3Transcription Factors (Transcription Factor)IBA
01/2021 - 04/2016
3oxidized low density lipoproteinIBA
01/2021 - 08/2012
3Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
01/2021 - 06/2017
3STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
01/2021 - 06/2019
3Cisplatin (Platino)FDA LinkGeneric
01/2021 - 05/2010
3AlkaloidsIBA
12/2020 - 06/2014
3Eukaryotic Initiation Factor-4F (EIF4F)IBA
01/2020 - 01/2016
3Glycoproteins (Glycoprotein)IBA
06/2019 - 11/2016
3Oxygen (Dioxygen)IBA
01/2019 - 06/2012
3Influenza Vaccines (Influenza Vaccine)FDA Link
01/2019 - 01/2018
3Dexamethasone (Maxidex)FDA LinkGeneric
10/2015 - 08/2003
3Threonine (L-Threonine)FDA Link
01/2012 - 01/2010
3Therapeutic UsesIBA
01/2011 - 08/2006
3Oxidants (Oxidizing Agents)IBA
08/2009 - 03/2009
2HDL LipoproteinsIBA
10/2022 - 01/2019
2Carrier Proteins (Binding Protein)IBA
02/2022 - 01/2018

Therapy/Procedure

23Therapeutics
04/2022 - 02/2007
7Radiotherapy
04/2022 - 06/2012
5Stents
01/2021 - 12/2010
5Drug Therapy (Chemotherapy)
12/2020 - 09/2010
3Aftercare (After-Treatment)
01/2017 - 07/2003
3Intravenous Injections
03/2011 - 01/2010